The CRKL Polyclonal Antibody from Bioss Inc. is a Rabbit Polyclonal antibody to CRKL. This antibody recognizes Human, Mouse, and Rat antigen. The CRKL Polyclonal Antibody has been validated for the following applications: Immunofluorescence, and Western Blot.
Description
This gene encodes a protein kinase containing SH2 and SH3 (src homology) domains which has been shown to activate the RAS and JUN kinase signaling pathways and transform fibroblasts in a RAS-dependent fashion. It is a substrate of the BCR-ABL tyrosine kinase, plays a role in fibroblast transformation by BCR-ABL, and may be oncogenic